Prostate Biopsy: Side Effects and Risks

UroToday – EAU 2007 – Session on Prostate Biopsy 1

The 7,074 biopsies were performed in 5,153 men. Minor complications included hematuria >1 day (13.8%), hematospermia (35.8%), and rectal bleeding (2.1%). Major complications were prostatitis, epididymitis, fever >38C, rectal bleeding >2 days, and urinary retention, all <1.0%. This study validates the safety of TRUS biopsy of the prostate.

This is a lower number than I would have guessed for blood in the semen (hematospermia), but a nice study to advise patients of possible side effects from a prostate biopsy.

This is what we need to consider when I asked the question of doing biopsies on everyone.

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10 Responses to Prostate Biopsy: Side Effects and Risks

  1. lu says:

    i had a prostate biopsy done 7 days ago i had sex and blood came out is this normal.

  2. Yes, hematospermia (blood in the semen) can take weeks and sometimes months to go away.

  3. Rick J says:

    I had a prostate biopsy yesterday. My doctor said it was fine to have sex today. I did and my semen appeared to be 99% blood. I went on-line to see if this is normal, and I read some recommendations to abstain from sex for 3-5 days. Several questions. Did I make a big mistake? Am I going to bleed to death? What happens if my prostate just keeps bleeding–will it come out somewhere to let me know? Help!

  4. Richard says:

    I had a prostrate biopsy 10 days ago now when I go to the bathroom (#2) I get a heavy reddish brown fluid from my penis is this normal

  5. Bowel movements put pressure on the prostate (or prostate area after surgery). This can cause some old blood to be pushed out of the prostate after a biopsy. You can have blood in the ejacualte for several weeks after a biopsy.
    If there is signs of infection (fevers, burning with urination, or other symptoms), you should contact your physician.

  6. bob r says:

    it’s been 5 weeks since my biospy and i still have blood in my semen. it is not as bad as in the beginning, is is getting closer to normal.

  7. Ken West says:

    I just had my 3rd prostate biopsy in 3 years, the last was just 6 months ago? My PSA is always high. I have history of prostate cancer in family. How often should biopsies be done? The prior two were false alarms.

  8. Domenico Savatta, M.D. says:

    It depends on multiple factors including the PSA value, how fast it is changing, and what the prior biopsies had in them exactly- high grade PIN or atypical cells.
    Things that can be done to assess prostate cancer risk are the free PA blood test, PCA3 urine test, and prostate MRIs.
    An experienced urologist should be able to help with this.

  9. John Clayton says:

    I had prostate biospy yesterday and two days later I am bleeding what I consider a good amount. No sex involved. Is this normal or something to be concerned about.

  10. Domenico Savatta, M.D. says:

    Bleeding is common and was described above. Your urologist should be available to answer questions if there is a concern.