Tag: active surveillance
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Study: Many men with prostate cancer can avoid early surgery – – UrologyTimes
Many men with prostate cancer do not need immediate treatment, especially if they have low PSA scores or low-risk tumors that are unlikely to grow and spread, according to a multicenter study that suggests such men who undergo radical prostatectomy fare no better than those undergoing observation. The study, published in the New England Journal…
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Prostate Cancer Screening: Moving Beyond PSA – Renal and Urology News
In nearly 1,000 men undergoing initial or repeat biopsy, these investigators found that urinary PCA3 prior to a prostate biopsy improved the prediction of PCa and high-grade disease with a high positive predictive value 90% in the initial biopsy setting and a high negative predictive value 88% in the repeat biopsy setting. The investigators conclude…
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5-ARI delays prostate cancer progression in men with low-risk disease – ModernMedicine
The 5-alpha-reductase inhibitor dutasteride Avodart appears to delay disease progression and the initiation of active treatment in men with low-risk, localized prostate cancer, results of a 3-year international clinical trial indicate.Treatment with dutasteride also reduces cancer-related anxiety, study authors found.”The results prove that using active surveillance plus dutasteride is a viable, safe, and effective treatment…
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Dutasteride Slows Prostate Cancer Progression – Renal and Urology News
ORLANDO—Dutasteride, a drug widely prescribed for treating benign prostatic enlargement, lowers the risk of prostate cancer PCa progression in men undergoing active surveillance for the disease, researchers concluded. via Dutasteride Slows Prostate Cancer Progression – Renal and Urology News. Dutasteride has been used for BPH and is thought to help reduce the risk of developing…
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MedWire News – Oncology – PCA3 predicts prostate tumor volume and could indicate AS suitability
MedWire News: Prostate cancer patients urinary prostate cancer antigen 3 PCA3 scores are strongly indicative of tumor volume, and could be a useful marker of suitability for treatment with active surveillance AS, study findings show. via MedWire News – Oncology – PCA3 predicts prostate tumor volume and could indicate AS suitability. I have been using…
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Robotic prostatectomy findings in patients with a single microfocus (5% or Less) of Gleason 6 Prostate Cancer at Biopsy
A Single Microfocus (5% or Less) of Gleason 6 Prostate Cancer at Biopsy-Can We Predict Adverse Pathological Outcomes? Source: Urotoday While a microfocus of Gleason score 6 prostate cancer on biopsy is commonly considered low risk disease, there was a greater than 1/5 risk of pathological upgrading and/or up staging. Patients with Gleason score 6…
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Determinants of Long-Term Retention of Prostate Cancer Patients in Active Surveillance Management Programs
From Urotoday and the AUA Of the 2134 PCa cases, 169 (7.9%) had AS as their initial management. Of the 169 AS cases, 89 (53%) remained untreated throughout follow-up (mean 7.1 years) and the remaining 47% received treatment an average of 3.1 years post-diagnosis. Significant predictors of eventual active treatment in multivariate models included younger…
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Active Surveillance for Prostate Cancer Patients
From Medscape May 12, 2008 — The urine test for the PCA3 gene, already marketed for use in diagnosing prostate cancer, could also be useful in prognostication. It might have clinical application in selecting men with low-grade and low-volume tumors who would be suitable candidates for active surveillance, say researchers writing in the May issue…
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Watchful waiting for prostate cancer
UroToday – European Urology – Watching the Face of Janus- Active Surveillance as a Strategy to Reduce Overtreatment for Localised Prostate Cancer A good abstract by Swedish urologists that addresses many of the issues for watchful waiting. It points out that the best candidates have a small amount of gleason 6 cancer. Most men did…